Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary TargetActivation of latent MMPs in vitro

General description

An organomercurial agent used for the activation of latent matrix metalloproteinases (MMPs) in vitro. Acts by facilitating the loss of the enzyme propeptide domain through an autolytic cleavage known as the cysteine switch.

Note: 1 set = 5 x 700 mg.

An organomercurial agent used for the activation of latent MMPs in vitro. Acts by facilitating the loss of the enzyme propeptide domain through an autolytic cleavage known as the cysteine switch.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Chen, J.-M., et al. 1991. J. Biol. Chem. 266, 5113.Marcy, A.I., et al. 1991. Biochemistry30, 6476.Stricklin, G.P., et al. 1983. Biochemistry22, 61.

Packaging

700 mg in Plastic Bag(s)

1 set in Fibre case

Reconstitution

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 month at 4°C.

Warning

Toxicity: Highly Toxic (H)